Epigenetic Landscapes Explain Partially Reprogrammed Cells and Identify Key Reprogramming Genes

Author Summary Traditionally, standard development has been viewed as a one-way process; an organism starts as a single cell (embryonic stem cell, ESC) that divides into a multitude of mature cell types (skin cells, heart, liver, etc). But, in 2006 Takahashi and Yamanaka revolutionized this view by…