Telomere shortening and DNA damage in culprit cells of different types of progressive fibrosing interstitial lung disease - PubMed

Pulmonary fibrosis is strongly associated with telomere shortening and increased DNA damage. Key cells in the pathogenesis involve alveolar type 2 (AT2) cells, club cells and myofibroblasts; however, to what extent these cells are affected by telomere shortening and DNA damage is not yet known. We s…