TLR ligand suppression or enhancement of Treg cells? A double-edged sword in immunity to tumours - Oncogene

Toll-like receptor (TLR) agonists are potent activators of innate immune responses, activating dendritic cell (DC) maturation and inflammatory cytokine secretion by innate immune cells and as a consequence they promote adaptive immune response when coadministered with foreign antigens. There is als…