Two FOXP3(+)CD4(+) T cell subpopulations distinctly control the prognosis of colorectal cancers - PubMed

CD4(+) T cells that express the forkhead box P3 (FOXP3) transcription factor function as regulatory T (Treg) cells and hinder effective immune responses against cancer cells. Abundant Treg cell infiltration into tumors is associated with poor clinical outcomes in various types of cancers. However, t…